Acute Toxicity Test Of The Green Viper Snake (Trimeresurus albolabris), Macroscopic Description Of The Kidney And Liver Of Mice (Mus musculus)

According to WHO (2010), the Trimeresurus albolabris snake is a venomous with high number of bite cases in Indonesia. Information on character and level toxicity venom Indonesia, including spp. snakes, still minimal. This study aims determine LD50 value (lethal dose 50), clinical symptoms, macroscopic appearance liver kidneys mice (Mus musculus) after being injected by white-lipped pit viper (Trimeresurus albolabris) venom. The subcutaneously into was 5,09 mg/kgBW. Clinical symptoms that appear increased movement activity, respiratory rate, lethargy, decreased reduced grooming. Macroscopic looks abnormal found (1) color changes form pale, pale yellowish, red spots (petechiae). (2) surface structure only one not flat. (3) consistency brittle easily. In kidney abnormal, pale. were nodules. easily soft.